New layout: you and your party are in the top-left, your weapons in the bottom-left.
Your character's name now shows above your health bar. Your level is on the portrait's bottom-left corner.
Health bars are segmented: small notches every 25 HP and bigger ones every 100, 500 and 1000. Damage you take trails behind as a fading ghost.
Ammo shows as individual rounds, and a reload refills them round by round.
Health numbers now appear when you hover a health bar. To always show them: Settings > Interface > "Always show player health values".
When you open the shop, a level-up offer or the orb store, the currency it uses flashes.
Shop cards now match the other perk cards: effect first, then flavour text, with tags.
Campfire
The difficulty obelisk now opens a carousel of cards. Each unlocked difficulty shows its enemy level and orb drop bonus, and the next locked one tells you how to unlock it.
Death
When you die, the camera stays on your body for 2 seconds. Then the Game Over screen opens, or in co-op the camera moves smoothly to a teammate.
Co-op
Each player's lamp now shows on every screen. When a player goes down, their lamp dims where they fell, so you no longer spectate in the dark.
A crown marks the host's portrait, and each guest has a green, yellow or red connection dot. Hover a teammate's portrait to see their character, weapons, gold, kills and perk cards.
Friend arrows now show each teammate's colour more accurately.
Weapon caches now give a weapon or nothing. They no longer give a weapon ascension when your slots are full.
Co-op Fixes (Guests)
Your character no longer slides after you stop moving, including near the map edge.
Ice-slowed enemies no longer jump back and forth.
Leaps and pounces now arc through the air instead of sliding along the ground.
The boss health bar and glow no longer jitter around the boss.
Enemy shots no longer freeze in mid-air at the end of a map.
If you leave a run and rejoin with the same room code, you're now told the run has already started. Before, you got stuck on the loading screen.