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PathogenicNewsBiweekly Update 11: UX Improvements
In-game event

Biweekly Update 11: UX Improvements

Pathogenic · published 30 Apr 2026, 16:00 UTC

All newsPlayers around this dateRead on Steam

Hi Parasites!

Hope you are enjoying the new battles with the Adaptive Immune System! We’ve received a lot of your feedback since the last patch, and today’s update will be focusing on addressing these concerns with a wide range of improvements on UX and gameplay balance.

Evolution Previews

The main change this time is the evolution preview function. You can now switch between all the different layouts and experiment with organelle combos when choosing your evolutions. Before confirming your evolution by pressing “Evolve”, you are free to swap to another evolution type and preview different outcomes.

UX Improvements

The community feedback has provided us with a spectrum of insights on how to make the gameplay more comfortable with everyone, and this patch includes a series of UX improvements to address some of the mentioned issues. Here are two of the more important ones:

Not sure which organelle to pick after a boss fight or in a room with organelle rewards? When picking up organelle rewards, as long as you don’t equip them on your pathogen, you can cancel the selection by quitting the editor panel! Though, do beware that mutation rewards do not benefit from this change and cannot be cancelled.

Some players also expressed confusion about the term “modifier”, as this word sometimes might be misinterpreted as an effect when we actually intended it to mean a specific type of organelle. We’ve renamed the term “infuser” to avoid further confusion.

Full Patch Notes

We’ve added many more improvements in this update, including easier seed sharing, better indication of important information, optimizations, and, as usual, numerous balance changes. For more details, please see our full patch notes below, and let us know what you think in the comments or in our Discord server!

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Main changes

  • Evolutions now give have a confirmation preview phase where you can try out different organelle builds

UX Improvements

  • You can cancel an organelle pickup before equipping

  • Warning when starting a run with empty organelle slots

  • Attack Modifiers renamed to Attack Infusers

  • Cursor size setting (small / normal / bigger / biggest)

  • The seed is now clickable to copy it to clipboard

  • Right stick scrolls menus on gamepad

  • Plasmid menu and shop flashes the cost when you can't afford an upgrade

  • Argentic Coating now shows current damage bonus

  • Flagella show their thrust power

  • Choose one rewards now show a "Choose" tooltip instead of "Pick Up"

Other Improvements

  • New explosion visuals for neutrophils

  • Improved lighting, enemies shouldn't overglow anymore

  • Codex loading times improved

  • Many CPU and GPU optimizations and stability optimizations, especially around level generation and panic recovery

  • Decreased zoom in the intestines

Balance Changes

  • Item rooms re-tuned: 1-item rooms rarer, 2-item rooms more common

  • Toxisome now spreads many toxins when triggered by Explosive Charge

  • Pyrosome damage slightly reduced

  • Photoreceptor attack speed increased

  • Dorsal Lysosome: Backstabs get detected more consistently now

  • Lateral Vent stamina cost reduced

  • Galvanic Infuser overcharge bonus slightly reduced

  • Stamina mutation is now more common

  • T-cell buffed enemies now take 4x less damage instead of 10x

  • T-cells also stick to and buff B-cells now, not just macrophages

  • Helper T-Cell HP: 600 -> 450

  • Helper T-Cell Armed HP: 800 -> 600

  • Dendritic cells no longer heal/buff each other

  • Dendritic Cell HP: 2000 -> 1400

  • Spawner Neutrophil HP: 550 -> 450

  • Kupffer Cell (boss) HP: 18500 -> 17500

  • Diphyllobothrium (segmented worm): only the head segment deals contact damage now; body segments are safe to touch

Fixes

  • When the player or a boss gets stuck in a wall, this gets automatically detected and the soft body gets pushed inside the room

  • Fixed audio volume sometimes getting stuck near zero after dying

  • Secondary key mapping persists after a save

More from Pathogenic

Other announcements

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