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PathogenicNewsBiweekly Update 01 - More Firepower
In-game event

Biweekly Update 01 - More Firepower

Pathogenic · published 20 Nov 2025, 17:40 UTC

All newsPlayers around this dateRead on Steam

Hi everyone,

Pathogenic's Demo will be getting a new patch every two weeks, starting with a bunch of new content today! In this update, we are bringing you new weapons, organelles, a new enemy and a range of rebalancing, optimizations and fixes.

New Weapons and Organelles

3 new weapons have been added to your arsenal. Your pathogen now has more firepower than ever before! (Try not to get hit by your own explosions though.)

  • Dehiscence Lobber: powerful bombs with a risk of friendly fire.

  • Cnidocyst: ties down target with a thread

  • Rotary Extruder: bullets go brrrrr when overcharged

11 new internal organelles have also been added for more interesting synergies in your build combos.

New Enemy

The Wave Macrophage joins the battle, mostly appearing in the Stomach area. It has a wide AOE attack and can be dangerous in tight spaces.

Patch Notes

Aside from new content, I've also been working on improving Pathogenic's gameplay with UI and visual updates, as well as balancing changes. See below for the full patch notes.

Content

New Weapons

  • Dehiscence Lobber

  • Rotary Extruder

  • Cnidocyst

New Internal Organelles

  • Magnetosome

  • Vesicle

  • Iridophore Membrane

  • Sympathetic Detonator

  • Refiner

  • Resonant Cavity

  • Turgosome

  • Phagosome

  • Starved Oxysome

  • Autophagic Mitochondrion

  • Endospore

New Enemy

  • Wave Macrophage

Balance and Gameplay

  • Chronosome now works with melee attacks

  • Reduced explosion scaling on Blastocyst Mortar

  • Slightly reduced max HP of The Wall and The Rock

  • Slightly reduced enemy HP scaling for each organ

  • Nerfed a couple of very hard rooms in the liver

  • Enemy bullets now disappear after beating the boss

  • Toxins disappear after finishing a room with Toxin Spreaders

  • Plasmid fragments are now attracted to you

  • Rooms spawning next to the start rooms are now even easier

Optimizations

  • Added control remapping and input icons matching the connected controller type

  • Added controller rumble

  • Improved Helmith jank, it should no longer tangle in itself and get stuck in walls

  • Added a screen transition animation

  • Significantly optimized level generation loading times

  • Graphics and physics optimizations

  • More graphics options

Visual improvements

  • Improved the distortion of the cells in walls

  • Added normal maps to special room hallway props

  • Added more vein props to rooms

  • Updated UI for the fast travel prompt

Localization

  • Russian and Finnish translations now available

More from Pathogenic

Other announcements

All news
In-game event7 Aug 2026New Patch: Balancing AdjustmentsHi Parasites! We're back with a new update! This time the focus is mostly on balancing. We've been combing through all your feedback here on Steam and on our Discord reporting channels, and we noticed a few organelles and mutations performing far better than intended due to how the buffs were stacked. This patch will turn them down a notch, while also buffing several other organelles to encoura…In-game event2 Aug 2026More Updates + The Demo Returns!Hey Parasites! Thursday July 30 marked the second week since Pathogenic launched and the end of our launch sale. Thanks to all of your support, these two weeks couldn’t have gone any better. We are truly grateful for everyone playing Pathogenic and sharing your thoughts on the game. We are getting plenty of feedback from the community every day, and will keep working on fixes and optimizations…In-game event22 Jul 2026Post-Launch Update: Addressing Player FeedbackHey Parasites! Pathogenic just passed 100k copies sold! Thank you so much for your support that helped us reach this massive milestone in less than a week after launch. Now for the more important thing of today: Pathogenic just got a new update with a series of rebalancing, optimizations and fixes! Balancing We've heard your feedback about the Lungs difficulty scaling. While it will remain as a…