In combat, your crosshair now reflects the range of your abilities.
The new drop-down in the bottom-right of the main menu sets your region. It will automatically set to that nearest to you. Selecting "Quick Match" will only match you with players from your region, and accepting an invite will place you in their region for that match.
Prior to this update, all traffic was routed through the US. International players connected as a client to their nearest region should see significantly reduced latency.