In the alternate future of Prey, President Kennedy survives the assassination, which sets off a turn of events leading to the central conflict.
https://www.youtube.com/watch?v=FXgarefKupc
After recovering from the attempt on his life, Kennedy threw his nation further into the space race by taking control of a U.S./Russian joint program and transforming a Russian satellite into a fully functional R&D facility meant to study non-terrestrials. This facility later became Talos I, a highly advanced space station owned by the TranStar Corporation. In just the scant few years since TranStar took over, the station has been used as the testing ground for some morally dubious experiments, with people on board serving as subjects – people like Morgan Yu. Discover more about the dark history of Talos I in the newly released alternate history video.