Timeline — box-select. Hold Alt and drag a rubber-band over the dope sheet to select, move, or delete many keys at once, across multiple tracks.
Timeline — exposure "on 1s/2s/3s…". New stopwatch button: pick several drawings and set how many frames each is held. The rest of the frames shift automatically.
Timeline — ease handles. Every transform key now has square handles you drag to set ease-in / ease-out right on the dope sheet.
New keys are smooth by default.
Brush settings are now global. Opening a project no longer resets your brush — your settings carry across projects. Reset them with "Reset to preset" or Reset All.
"Reset to preset" button in Tool Settings (Brush / Eraser) — quickly revert the current tool to its selected preset.
"Crop to Drawing" in the Inspector — shrink a layer down to the bounds of its artwork.
New layers appear at the top of the layer list.
AutoKey is on by default on the timeline — transform and paint edits key the current frame automatically.
Fixes
The paint color no longer resets when you switch brushes — your color stays.
Selection now maps correctly on rotated layers (both rectangle and ellipse).
A selection made of several separate pieces now outlines every piece, not just one.
Onion skin no longer shows on a layer that has it turned off in the timeline.
Animated layers no longer drift when you change their parent.
The transform gizmo center is now visible on light backgrounds (was blending into white).
Reset All now resets every tool (brush, eraser, fill, liquify), not just the brush.
Drawing on a freshly created frame no longer stutters.